{"id":25,"date":"2023-08-06T16:26:44","date_gmt":"2023-08-06T16:26:44","guid":{"rendered":"http:\/\/renewed.napdi-cds.org\/?page_id=25"},"modified":"2025-03-26T20:47:41","modified_gmt":"2025-03-26T20:47:41","slug":"apps","status":"publish","type":"page","link":"https:\/\/napdi-cds.org\/?page_id=25","title":{"rendered":"(Experimental) Apps"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">NOTE: These SMART apps are experimental and are NOT intended to offer medical advice at this time. Please consult a physician and\/or pharmacist if you are concerned about a possible natural product-drug interaction.  <\/h2>\n\n\n\n<p>Welcome to the NAPDI-CDS app page.  Tools to improve patient safety are listed below.  These are based on our NAPDI-CDS algorithms using open, free, and standards-based health information technology standards (SMART on FHIR).  <\/p>\n\n\n<div class=\"wp-block-ub-content-toggle wp-block-ub-content-toggle-block\" id=\"ub-content-toggle-block-83c8748c-e441-4fc7-ba14-2434fb881e4f\" data-mobilecollapse=\"true\" data-desktopcollapse=\"true\" data-preventcollapse=\"false\" data-showonlyone=\"false\">\n<div class=\"wp-block-ub-content-toggle-accordion\" style=\"border-color: #f1f1f1; \" id=\"ub-content-toggle-panel-block-\">\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-title-wrap\" style=\"background-color: #f1f1f1;\" aria-controls=\"ub-content-toggle-panel-0-83c8748c-e441-4fc7-ba14-2434fb881e4f\" tabindex=\"0\">\n\t\t\t<p class=\"wp-block-ub-content-toggle-accordion-title ub-content-toggle-title-83c8748c-e441-4fc7-ba14-2434fb881e4f\" style=\"color: #000000; \">NPDI-CDS for Cannabidiol &#8211; Direct Oral Anticoagulants(DOACs)<\/p>\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-toggle-wrap right\" style=\"color: #000000;\"><span class=\"wp-block-ub-content-toggle-accordion-state-indicator wp-block-ub-chevron-down\"><\/span><\/div>\n\t\t<\/div>\n\t\t\t<div role=\"region\" aria-expanded=\"false\" class=\"wp-block-ub-content-toggle-accordion-content-wrap ub-hide\" id=\"ub-content-toggle-panel-0-83c8748c-e441-4fc7-ba14-2434fb881e4f\">\n\n<p>We have built a SMART app to support clinician decision making for situations where a patient is at risk for an adverse event due to DOAC toxicity caused by inhibition of the metabolism of DOAC by an inhibitor of P-glycoprotein(P-gp). <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1725\" height=\"416\" src=\"http:\/\/napdi-cds.org\/wp-content\/uploads\/2023\/11\/DOAC-CBD-app.png\" alt=\"\" class=\"wp-image-119\"><\/figure>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<ul class=\"wp-block-list\">\n<li>You can try the app out yourself by clicking on any of the following patient profiles\n<ul class=\"wp-block-list\">\n<li><a href=\"http:\/\/cbd.napdi-cds.org\/launchStandalone?ddi=cbd_doac&amp;patient=100005\" target=\"_blank\" rel=\"noreferrer noopener\">Patient on <strong>dabigatran<\/strong><\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/cbd.napdi-cds.org\/launchStandalone?ddi=cbd_doac&amp;patient=100008\" target=\"_blank\" rel=\"noreferrer noopener\">Patient on <strong>apixaban<\/strong><\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/cbd.napdi-cds.org\/launchStandalone?ddi=cbd_doac&amp;patient=100006\" target=\"_blank\" rel=\"noreferrer noopener\">Patient on <strong>rivaroxaban<\/strong><\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/cbd.napdi-cds.org\/launchStandalone?ddi=cbd_doac&amp;patient=100007\" target=\"_blank\" rel=\"noreferrer noopener\">Patient on <strong>edoxaban<\/strong><\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<p><strong>Please provide us with feedback!<\/strong><\/p>\n\n\n\n<p>Email us at <a rel=\"noreferrer noopener\" href=\"mailto:info@napdi-cds.org\" target=\"_blank\"><strong>info@napdi-cds.org<\/strong><\/a><\/p>\n\n<\/div>\n\t\t<\/div>\n\n<div class=\"wp-block-ub-content-toggle-accordion\" style=\"border-color: #f1f1f1; \" id=\"ub-content-toggle-panel-block-\">\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-title-wrap\" style=\"background-color: #f1f1f1;\" aria-controls=\"ub-content-toggle-panel-1-83c8748c-e441-4fc7-ba14-2434fb881e4f\" tabindex=\"0\">\n\t\t\t<p class=\"wp-block-ub-content-toggle-accordion-title ub-content-toggle-title-83c8748c-e441-4fc7-ba14-2434fb881e4f\" style=\"color: #000000; \">NPDI-CDS for Cannabidiol &#8211; Clopidogrel<\/p>\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-toggle-wrap right\" style=\"color: #000000;\"><span class=\"wp-block-ub-content-toggle-accordion-state-indicator wp-block-ub-chevron-down\"><\/span><\/div>\n\t\t<\/div>\n\t\t\t<div role=\"region\" aria-expanded=\"false\" class=\"wp-block-ub-content-toggle-accordion-content-wrap ub-hide\" id=\"ub-content-toggle-panel-1-83c8748c-e441-4fc7-ba14-2434fb881e4f\">\n\n<p>We have built a SMART app to support clinician decision making for situations where a patient is at risk for an adverse event due to reduced clopidogrel efficacy caused by inhibition of the metabolism of clopidogrel to an active drug by an inhibitor of cytochrome P450 2C19. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1857\" height=\"479\" src=\"http:\/\/napdi-cds.org\/wp-content\/uploads\/2023\/11\/Clopidogrel_CBD-app.png\" alt=\"\" class=\"wp-image-120\"><\/figure>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<ul class=\"wp-block-list\">\n<li>You can try the app out yourself by clicking on any of the following patient profiles\n<ul class=\"wp-block-list\">\n<li><a href=\"http:\/\/cbd.napdi-cds.org\/launchStandalone?ddi=cbd_clopidogrel&amp;patient=100010\" target=\"_blank\" rel=\"noreferrer noopener\">Patient on <strong>clopidogrel<\/strong><\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<p><strong>Please provide us with feedback!<\/strong><\/p>\n\n\n\n<p>Email us at <a rel=\"noreferrer noopener\" href=\"mailto:info@napdi-cds.org\" target=\"_blank\"><strong>info@napdi-cds.org<\/strong><\/a><\/p>\n\n<\/div>\n\t\t<\/div>\n\n<div class=\"wp-block-ub-content-toggle-accordion\" style=\"border-color: #f1f1f1; \" id=\"ub-content-toggle-panel-block-\">\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-title-wrap\" style=\"background-color: #f1f1f1;\" aria-controls=\"ub-content-toggle-panel-2-83c8748c-e441-4fc7-ba14-2434fb881e4f\" tabindex=\"0\">\n\t\t\t<p class=\"wp-block-ub-content-toggle-accordion-title ub-content-toggle-title-83c8748c-e441-4fc7-ba14-2434fb881e4f\" style=\"color: #000000; \">NPDI-CDS for Cannabidiol &#8211; Warfarin<\/p>\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-toggle-wrap right\" style=\"color: #000000;\"><span class=\"wp-block-ub-content-toggle-accordion-state-indicator wp-block-ub-chevron-down\"><\/span><\/div>\n\t\t<\/div>\n\t\t\t<div role=\"region\" aria-expanded=\"false\" class=\"wp-block-ub-content-toggle-accordion-content-wrap ub-hide\" id=\"ub-content-toggle-panel-2-83c8748c-e441-4fc7-ba14-2434fb881e4f\">\n\n<p>We have built a SMART app to support clinician decision making for situations where a patient is at risk for an adverse event due to warfarin toxicity caused by inhibition of the metabolism of warfarin by an inhibitor of cytochrome P450 2C9. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1740\" height=\"431\" src=\"http:\/\/napdi-cds.org\/wp-content\/uploads\/2023\/11\/Warfarin-CBD-app.png\" alt=\"\" class=\"wp-image-121\"><\/figure>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<ul class=\"wp-block-list\">\n<li>You can try the app out yourself by clicking on any of the following patient profiles\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/cbd.napdi-cds.org\/launchStandalone?ddi=cbd_warfarin&amp;patient=100009\">Patient on <\/a><strong><a href=\"http:\/\/cbd.napdi-cds.org\/launchStandalone?ddi=cbd_warfarin&amp;patient=100009\" target=\"_blank\" rel=\"noreferrer noopener\">warfarin<\/a><\/strong><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<p><strong>Please provide us with feedback!<\/strong><\/p>\n\n\n\n<p>Email us at <a rel=\"noreferrer noopener\" href=\"mailto:info@napdi-cds.org\" target=\"_blank\"><strong>info@napdi-cds.org<\/strong><\/a><\/p>\n\n<\/div>\n\t\t<\/div>\n\n<div class=\"wp-block-ub-content-toggle-accordion\" style=\"border-color: #f1f1f1; \" id=\"ub-content-toggle-panel-block-\">\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-title-wrap\" style=\"background-color: #f1f1f1;\" aria-controls=\"ub-content-toggle-panel-3-83c8748c-e441-4fc7-ba14-2434fb881e4f\" tabindex=\"0\">\n\t\t\t<p class=\"wp-block-ub-content-toggle-accordion-title ub-content-toggle-title-83c8748c-e441-4fc7-ba14-2434fb881e4f\" style=\"color: #000000; \">NPDI-CDS for Kratom &#8211; Oxycodone<\/p>\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-toggle-wrap right\" style=\"color: #000000;\"><span class=\"wp-block-ub-content-toggle-accordion-state-indicator wp-block-ub-chevron-down\"><\/span><\/div>\n\t\t<\/div>\n\t\t\t<div role=\"region\" aria-expanded=\"false\" class=\"wp-block-ub-content-toggle-accordion-content-wrap ub-hide\" id=\"ub-content-toggle-panel-3-83c8748c-e441-4fc7-ba14-2434fb881e4f\">\n\n<p>We have built a SMART app to support clinician decision making for situations where a patient is at risk for an adverse event due to oxycodone toxicity caused by inhibition of the metabolism of oxycodone by an inhibitor of cytochrome P450 2D6.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"387\" src=\"https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1024x387.png\" alt=\"\" class=\"wp-image-273\" srcset=\"https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1024x387.png 1024w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-300x113.png 300w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-768x290.png 768w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1536x581.png 1536w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-800x302.png 800w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image.png 1894w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<ul class=\"wp-block-list\">\n<li>You can try the app out yourself by clicking on any of the following patient profiles\n<ul class=\"wp-block-list\">\n<li><strong><a href=\"http:\/\/kratom.napdi-cds.org\/launchStandalone?ddi=kratom&amp;patient=100011\">Kratom constituent mitragynine-Oxycodone<\/a><\/strong><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<p><strong>Please provide us with feedback!<\/strong><\/p>\n\n\n\n<p>Email us at <a href=\"mailto:info@napdi-cds.org\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>info@napdi-cds.org<\/strong><\/a><\/p>\n\n<\/div>\n\t\t<\/div>\n\n<div class=\"wp-block-ub-content-toggle-accordion\" style=\"border-color: #f1f1f1; \" id=\"ub-content-toggle-panel-block-\">\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-title-wrap\" style=\"background-color: #f1f1f1;\" aria-controls=\"ub-content-toggle-panel-4-83c8748c-e441-4fc7-ba14-2434fb881e4f\" tabindex=\"0\">\n\t\t\t<p class=\"wp-block-ub-content-toggle-accordion-title ub-content-toggle-title-83c8748c-e441-4fc7-ba14-2434fb881e4f\" style=\"color: #000000; \">NPDI-CDS for Kratom &#8211; Quetiapine<\/p>\n\t\t\t<div class=\"wp-block-ub-content-toggle-accordion-toggle-wrap right\" style=\"color: #000000;\"><span class=\"wp-block-ub-content-toggle-accordion-state-indicator wp-block-ub-chevron-down\"><\/span><\/div>\n\t\t<\/div>\n\t\t\t<div role=\"region\" aria-expanded=\"false\" class=\"wp-block-ub-content-toggle-accordion-content-wrap ub-hide\" id=\"ub-content-toggle-panel-4-83c8748c-e441-4fc7-ba14-2434fb881e4f\">\n\n<p>We have built a SMART app to support clinician decision making for situations where a patient is at risk for an adverse event due to quetiapine toxicity caused by inhibition of the metabolism of quetiapine by an inhibitor of cytochrome P450 3A4 and additive CNS effects.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"447\" src=\"https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1-1024x447.png\" alt=\"\" class=\"wp-image-274\" srcset=\"https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1-1024x447.png 1024w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1-300x131.png 300w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1-768x335.png 768w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1-1536x671.png 1536w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1-800x349.png 800w, https:\/\/napdi-cds.org\/wp-content\/uploads\/2025\/03\/image-1.png 1891w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<ul class=\"wp-block-list\">\n<li>You can try the app out yourself by clicking on any of the following patient profiles\n<ul class=\"wp-block-list\">\n<li><strong><a href=\"http:\/\/kratom.napdi-cds.org\/launchStandalone?ddi=kratomQ&amp;patient=100012\">Kratom constituent mitragynine-Quetiapine<\/a><\/strong><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<p><strong>Please provide us with feedback!<\/strong><\/p>\n\n\n\n<p>Email us at <a href=\"mailto:info@napdi-cds.org\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>info@napdi-cds.org<\/strong><\/a><\/p>\n\n<\/div>\n\t\t<\/div>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\">Acknowledgements<\/h3>\n\n\n\n<p>Funding for developing the NPDI-CDS apps came from grant U54 AT008909 from the National Institutes of Health National Center for Complementary and Integrative Health (NCCIH) as part of  the Center of Excellence for Natural Product Drug Interaction Research (<a href=\"http:\/\/napdicenter.org\">NaPDI Center<\/a>). Additional funding provided by U18 HS027099, R01HS025984 and R21HS023826 from the Agency for Healthcare Research and Quality (AHRQ).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>NOTE: These SMART apps are experimental and are NOT intended to offer medical advice at this time. Please consult a physician and\/or pharmacist if you are concerned about a possible natural product-drug interaction. Welcome to the NAPDI-CDS app page. Tools to improve patient safety are listed below. These are based on our NAPDI-CDS algorithms using open, free, and standards-based health information technology standards (SMART on FHIR). Acknowledgements Funding for developing<\/p>\n<p><a class=\"more-link\" href=\"https:\/\/napdi-cds.org\/?page_id=25\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-25","page","type-page","status-publish","hentry"],"featured_image_src":null,"_links":{"self":[{"href":"https:\/\/napdi-cds.org\/index.php?rest_route=\/wp\/v2\/pages\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/napdi-cds.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/napdi-cds.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/napdi-cds.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/napdi-cds.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25"}],"version-history":[{"count":18,"href":"https:\/\/napdi-cds.org\/index.php?rest_route=\/wp\/v2\/pages\/25\/revisions"}],"predecessor-version":[{"id":275,"href":"https:\/\/napdi-cds.org\/index.php?rest_route=\/wp\/v2\/pages\/25\/revisions\/275"}],"wp:attachment":[{"href":"https:\/\/napdi-cds.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}